Top Non-Aspirin Pain Relievers for Pain Relief

The best Non-aspirin Pain Relievers includes Tylenol Extra Strength Gelcaps [100 ct], Amazon Basic Care Ibuprofen 200 mg [500 Count], Tylenol Extra Strength 500 mg Caplets [100 Ct] and many others as mentioned below.

1

Tylenol Extra Strength Gelcaps [100 ct]

  • 100-count for extended pain relief.
  • 500 mg acetaminophen per gelcap.
  • Rapid release for fast-acting relief.
  • Laser-drilled holes enhance absorption speed.
  • Relieves headaches, muscle pain, and fever.
  • Gentle on the stomach.
  • Recommended by doctors for pain relief.
  • Average Rating out of 5:
  • Price Range: $12.40
2

Amazon Basic Care Ibuprofen 200 mg [500 Count]

  • Contains 200 mg of ibuprofen per tablet.
  • Effective pain reliever and fever reducer.
  • Relieves headaches, body aches, and arthritis pain.
  • Alleviates menstrual cramps and toothaches effectively.
  • No prescription needed for strong relief.
  • Recommended for adults and children 12 years and older.
  • May be manufactured in India or U.S.
  • Average Rating out of 5:
  • Price Range: $8.79
3

Tylenol Extra Strength 500 mg Caplets [100 Ct]

  • 100-count bottle for effective pain relief.
  • 500 mg acetaminophen per caplet for strong relief.
  • Relieves headaches, backaches, and toothaches.
  • Reduces fever and alleviates minor arthritis pain.
  • Recommended for adults and children 12+ years.
  • Take two caplets every six hours as needed.
  • From the #1 doctor recommended pain relief brand.
  • Average Rating out of 5:
  • Price Range: $10.94
4

Amazon Basic Care Acetaminophen 500 mg [500 Count]

  • Active ingredient: Acetaminophen, 500 mg per caplet.
  • Relieves minor aches and pains effectively.
  • Temporarily reduces fever for adults and children.
  • Compare to Extra Strength Tylenol Caplets.
  • Includes 500 count for extended use.
  • Packaging may vary based on availability.
  • Manufactured in India or the U.S.
  • Average Rating out of 5:
  • Price Range: $9.59
5

Tylenol Arthritis Pain Relief Caplets [100 ct.]

  • Fast-acting relief for arthritis and joint pain.
  • Contains 650 mg acetaminophen per caplet.
  • Temporary relief for minor arthritis discomfort.
  • Effective fever reducer for added comfort.
  • Bi-layer design for lasting 8-hour relief.
  • Adult use: take two caplets every 8 hours.
  • #1 doctor recommended pain relief brand.
  • Average Rating out of 5:
  • Price Range: $12.44
6

Advil Pain Reliever [100 Coated Tablets]

  • Effective pain relief with 200mg ibuprofen.
  • Relieves headaches, backaches, and menstrual pain.
  • Coated tablets for easy swallowing.
  • Lasts up to 6 hours per dose.
  • Reduces fever and targets inflammation.
  • HSA and FSA eligible product.
  • New packaging with 20% less plastic.
  • Average Rating out of 5:
  • Price Range: $9.85
7

Tylenol PM Extra Strength Sleep Aid [100 ct]

  • 100-count bottle for extended use.
  • Non-habit forming sleep aid for restful nights.
  • Relieves nighttime aches and pains effectively.
  • Contains 500 mg acetaminophen for pain relief.
  • Features 25 mg diphenhydramine HCl for sleep.
  • Recommended for adults and children 12 and older.
  • Helps you fall asleep fast and stay asleep.
  • Average Rating out of 5:
  • Price Range: $13.97
8

Tylenol Children's Pain & Fever Medicine [8 Fl. Oz]

  • Dye-free formula for sensitive tummies.
  • Cherry flavor kids love.
  • Temporarily relieves minor aches and pains.
  • Reduces fever in as little as 15 minutes.
  • Safe for children ages 2-11 years.
  • Acetaminophen-based pain and fever relief.
  • Pediatrician recommended for effective care.
  • Average Rating out of 5:
  • Price Range: $11.47
9

Motrin Children's Ibuprofen Oral Suspension [100mg]

  • Relieves fever and minor aches effectively.
  • Dye-free berry flavor for easy consumption.
  • Contains 100mg ibuprofen per 5mL dose.
  • Suitable for children aged 2 to 11 years.
  • Provides up to 8 hours of relief.
  • Includes dosing cup for easy administration.
  • Trusted brand for pain and fever relief.
  • Average Rating out of 5:
  • Price Range: $10.49
10

Tylenol Extra Strength Dissolve Packs [32 ct]

  • 32 dissolve packs for convenient pain relief.
  • 500 mg acetaminophen for effective pain management.
  • Berry flavor for a pleasant taste experience.
  • No water needed, dissolves on the tongue.
  • Relieves minor aches and pains quickly.
  • Ibuprofen- and aspirin-free for safe use.
  • Recommended by doctors for pain relief.
  • Average Rating out of 5:
  • Price Range: $12.96
11

Tylenol Infants Pain & Fever Relief (2 FL OZ)

  • Dye-free formula for sensitive tummies.
  • Cherry flavor makes it easy to administer.
  • 160 mg acetaminophen per 5 mL dose.
  • Relieves fever within 15 minutes.
  • Recommended by pediatricians for pain relief.
  • Safe for infants ages 2-3 years.
  • Includes easy-to-use dosing syringe.
  • Average Rating out of 5:
  • Price Range: $9.49
12

Advil Liqui-Gels Mini Pain Reliever (200mg)

  • 200mg Ibuprofen for effective pain relief.
  • Fast-absorbing Liqui-Gels for quick action.
  • Mini size, easy to swallow capsules.
  • Relieves headaches, back pain, and arthritis pain.
  • Comparable strength to regular Advil Liqui-Gels.
  • Ideal for college dorm room essentials.
  • HSA and FSA eligible product.
  • Average Rating out of 5:
  • Price Range: $23.11
13

Advil Pain Reliever (200mg, 100 Tablets)

  • Fast-acting relief from pain and inflammation.
  • Provides up to 8 hours of lasting comfort.
  • Doctor-recommended brand for trusted effectiveness.
  • Gentle on the stomach for easy digestion.
  • Conveniently individually wrapped 200 mg tablets.
  • Ideal for headaches, backaches, and menstrual pain.
  • Easy to carry for on-the-go relief.
  • Average Rating out of 5:
  • Price Range: $11.28
14

Amazon Basic Care Naproxen Sodium 220 mg (300 Count)

  • Active ingredient: 220 mg Naproxen Sodium.
  • Relieves pain and reduces fever effectively.
  • Lasts up to 12 hours per dose.
  • Relieves headaches, toothaches, and muscular pain.
  • Suitable for adults and children over 12.
  • Gluten-free, capsule-shaped tablets for easy swallowing.
  • Comparable to Aleve for effective pain relief.
  • Average Rating out of 5:
  • Price Range: $13.47
15

Tylenol Children's Chewables, Grape Flavor [24 ct]

  • Effective relief for kids' minor aches and pains.
  • Contains 160 mg of acetaminophen per tablet.
  • Temporarily reduces fever and alleviates cold symptoms.
  • Aspirin-free and ibuprofen-free formula for safety.
  • Delicious grape flavor that kids love.
  • Recommended for children ages 2 to 11 years.
  • Trusted by parents for over 60 years.
  • Average Rating out of 5:
  • Price Range: $7.98
16

Motrin IB Ibuprofen 200mg [225 ct] Pain Reliever

  • Effective relief for minor aches and pains.
  • Contains 200 mg of ibuprofen per tablet.
  • Reduces fever and alleviates cold symptoms.
  • Relieves headaches, backaches, and menstrual cramps.
  • Convenient value size with 225 tablets.
  • Trustworthy brand with a history of effectiveness.
  • Easy dosing for adults and children over 12.
  • Average Rating out of 5:
  • Price Range: $13.99
17

Amazon Basic Care Extra Strength Acetaminophen (100 ct)

  • Contains 500 mg acetaminophen per caplet.
  • Relieves minor aches and pains effectively.
  • Fast-acting fever reducer for temporary relief.
  • Suitable for adults and children over 12.
  • Aspirin, caffeine, and gluten free formulation.
  • Child-resistant packaging for safety.
  • Manufactured in India or the U.S.
  • Average Rating out of 5:
  • Price Range: $3.92
18

Motrin Infants' Ibuprofen Drops [1 FL OZ]

  • Liquid ibuprofen drops for infants in berry flavor.
  • Temporarily relieves minor aches and pains.
  • Effective fever reducer for infants 6 to 23 months.
  • Dye-free and alcohol-free concentrated medicine drops.
  • Provides relief for up to 8 hours.
  • Easy dosing with included infant medicine syringe.
  • Trusted brand for effective pain and fever relief.
  • Average Rating out of 5:
  • Price Range: $9.74
19

Amazon Basic Care Children's Ibuprofen 100 mg (8 fl oz)

  • Contains 100 mg ibuprofen per 5 mL dose.
  • Effective pain reliever and fever reducer.
  • Berry flavor, appealing to children.
  • Designed for ages 2 to 11 years.
  • Child-resistant safety cap for protection.
  • Provides relief for up to 8 hours.
  • Gluten-free and alcohol-free formulation.
  • Average Rating out of 5:
  • Price Range: $7.49
20

Amazon Basic Care Children’s Ibuprofen 100 mg [24 Count]

  • Contains 100 mg of ibuprofen per tablet.
  • Convenient chewable tablets for easy consumption.
  • Helps relieve minor aches and pains.
  • Effective fever reducer for children ages 2-11.
  • Child-friendly orange flavor for pleasant taste.
  • Dye-free and preservative-free formulation.
  • Provides relief that lasts up to 8 hours.
  • Average Rating out of 5:
  • Price Range: $5.84
21

Amazon Basic Care Acetaminophen 650 mg [400 Count]

  • Provides effective pain relief for arthritis.
  • Contains 650 mg of acetaminophen per tablet.
  • Extended-release formula for long-lasting relief.
  • Aspirin-free and gluten-free formulation.
  • Child-resistant cap for safety.
  • Temporarily relieves various minor aches and pains.
  • Consult a doctor for those under 18 years.
  • Average Rating out of 5:
  • Price Range: $21.08
22

Amazon Basic Care Ibuprofen Tablets 200 mg (100 Count)

  • 200 mg ibuprofen per tablet for effective pain relief.
  • Relieves headaches, muscular aches, and arthritis pain.
  • Also helps with toothaches and menstrual cramps.
  • Gluten-free coated tablets for easy swallowing.
  • Nonsteroidal anti-inflammatory drug (NSAID) formula.
  • No prescription needed for proven pain relief.
  • Doctor recommended over-the-counter pain relief option.
  • Average Rating out of 5:
  • Price Range: $5.36
23

A+Health Ibuprofen 200 Mg Softgels [300 Count]

  • Contains 200mg of Ibuprofen per softgel.
  • Effective pain reliever and fever reducer.
  • Relieves headaches, toothaches, and backaches.
  • Helps with menstrual cramps and muscular aches.
  • 300 softgels provide great value for relief.
  • Nonsteroidal anti-inflammatory drug (NSAID) formula.
  • Easy-to-swallow liquid-filled softgels.
  • Average Rating out of 5:
  • Price Range: $14.69
24

Amazon Basic Care Children's Acetaminophen 160 mg

  • Contains 160 mg acetaminophen per 5 mL.
  • Grape flavor for pleasant taste.
  • Relieves minor aches and pains.
  • Temporarily reduces fever effectively.
  • Aspirin, ibuprofen, alcohol, and gluten free.
  • Child-resistant safety cap for protection.
  • Compare to Children's Tylenol Oral Suspension.
  • Average Rating out of 5:
  • Price Range: $4.09
25

Amazon Basic Care Ibuprofen 200 mg [100 Count]

  • 200 mg ibuprofen per caplet for effective pain relief.
  • Relieves headaches, arthritis, toothaches, and backaches.
  • Temporarily reduces fever for added comfort.
  • Coated caplets for easy swallowing and digestion.
  • Approved for adults and children aged 12 and over.
  • Gluten-free formulation suitable for dietary needs.
  • Child-resistant packaging for safety and security.
  • Average Rating out of 5:
  • Price Range: $4.72
26

Alka-Seltzer Hangover Relief Tablets [60 Count]

  • Fast relief starts in about 15 minutes.
  • Effervescent tablets dissolve easily in water.
  • Formulated with aspirin and caffeine for effectiveness.
  • Great for hangovers, headaches, and body aches.
  • Perfect for party favors and events.
  • Orange-flavored fizzy drink for enjoyable hydration.
  • Convenient pocket-sized packets for on-the-go relief.
  • Average Rating out of 5:
  • Price Range: $12.43
27

Advil Liqui-Gels Pain Reliever [200 Capsules]

  • 200 liquid-filled capsules for effective pain relief.
  • Contains 200mg ibuprofen for fast-acting results.
  • Relieves headaches, backaches, and menstrual pain.
  • Also effective for joint pain and muscle aches.
  • Suitable for adults and children 12 years and older.
  • HSA and FSA eligible for health savings.
  • Fast absorption for rapid relief from discomfort.
  • Average Rating out of 5:
  • Price Range: $23.49
28

Tylenol Infants Acetaminophen Liquid (1 fl. oz)

  • Relieves minor aches and pains effectively.
  • Quickly reduces fever in 15 minutes.
  • Dye-free cherry flavor for enjoyable taste.
  • Gentle on little tummies, ibuprofen-free.
  • Includes SimpleMeasure dosing syringe for accuracy.
  • Pediatrician-recommended for infants’ pain relief.
  • Suitable for children aged 2-3 years.
  • Average Rating out of 5:
  • Price Range: $6.29
29

Advil Pain Reliever & Sleep Aid [300 Count]

  • 300 count for long-lasting pain relief.
  • Includes both pain reliever and sleep aid.
  • Ibuprofen 200mg for effective pain management.
  • Coated tablets for easy swallowing.
  • Helps with headaches, arthritis, and back pain.
  • Nighttime formula promotes restful sleep.
  • New packaging reduces plastic waste significantly.
  • Average Rating out of 5:
  • Price Range: $23.49